International Food Research Journal 23(6): (December ). Journal Effect of belimbing buluh (Averrhoa bilimbi) juice extract on oxidative. Journal of Food and Drug Analysis . ABAEE = ethyl acetate fraction of Averrhoa bilimbi Linn fruits; DM = diabetes mellitus; DM + ABAEE = STZ-induced. The Combination of Belimbing Wuluh Fruit (Averrhoa Bilimbi L.) and Leaves of Tapak Dara (Catharanthus Roseus G.) From Indonesia as a.

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Dry discs were aseptically placed on NA. Phytochemical screenings, thrombolytic activity and antimicrobial properties of the bark extracts of Averrhoa bilimbi. It was found to show significant hypoglycemic as well biliimbi its antioxidative property which can be used against the oxidative stress and consecutive heart disease, stroke, cancer, and liver damage. Evaluation of total phenolic content, free radical scavenging activity and phytochemical screening of different extracts of Averrhoa bilimbi fruits Int Curr Pharm J.

The key emphasis of this review article is to establish averrha utilitarian side and medicinal characteristic of A.

The zones of inhibition observed averdhoa the disc diffusion assay are shown in the Table 1. In-vitro antioxidant and cytotoxic potential od hydromethanolic extract of Averrhoa bilimbi L.

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However, these organic solvents have also been feasibly associated to generate cancer or other deleterious toxicities in the human body. User Username Password Remember me. Journall The preliminary phytochemical screening of the leaves extracts revealed the presence of alkaloid, tannins, billimbi, flavonoids, cardiac glycosides, glycosides, triterpenes, phenols, and carbohydrates.

For instance, the supercritical fluid extraction SFE technique might be used to make toxic solvent free A. The flowers are heterotristylous with petal 10—30 m long, yellowish green to reddish purple.

Impact Cites per doc – 0. All rats were housed in aluminum cages, placed in a room with a temperature of ,5 0 C and fairly light. All the bacteria were sub-cultured on nutrient agar for inoculation. Hence, this review targets at emphasizing the diverse traditional claims and pharmacological activities of A. Isolation and characterization of bioactive compounds of different parts of A. Blood glucose measurement results are shown averhoa Table 1.


The extract aevrrhoa animals also showed minimal signs of histological changes and dermatitis compared with the untreated group. Pharmacological investigations have revealed that A. Winarti C, Marwati T. Traditionally, the leaves are used as paste on itches, swelling, skin eruptions, cough, sites of poisonous, etc. Diabetes mellitus is defined as a group metabolic disease by hyperglycemia, resulting in a defective secretion of insulin, action of insulin, or both 1.

Then extracts were dried with a rotary evaporator. It has compound leaves with twenty—forty leaflets each and 5—10 cm long. Extensive pharmacological bipimbi conducted over the years have proven the scientific bases for the therapeutic uses of A. Moreover, a particular plant of medicinal quality needs to be processed very carefully to preserve the pharmacological activity and threshold amount of the bioactive compounds from pre- and post-harvesting stress such as ultraviolet light, heat, chemical exposure, microorganisms attack, and moisture.

However, extracts from younger fruits are more effective against the bacteria. Antioxidant and nitric oxide inhibition activities of selected Malay traditional vegetables.

Averrhoa bilimbi Linn.: A review of its ethnomedicinal uses, phytochemistry, and pharmacology

The authors would like to thank to the Department of Higher education of Indonesia as our funders. Bioprocessing of Averrhoa bilimbi Since time immemorial, medicinal plants have been the reliable source for the herbal and traditional medicine practitioners to treat various disorders without even knowing about the presence of active principles responsible for the assuagement of symptoms of the disease in the plants.

Blood glucose levels were measured on days 0, 5, 7, 9, 13, and Screening of cholesterol uptake inhibitor from Thai medicinal plant extracts. Role of Averrhoa bilimbi as an Anticancer Agent Cytotoxicity assays are used to determine whether a compound or extract is toxic to cells. The major compounds were nonanal 2.


The decoction of fruits is also treating inflammatory conditions including hepatitis, fever and diarrhea. Therefore, this reason alone rescinds the potential of bilibi preparations that are prepared using toxic organic solvents. Young stage of A.

Antimicrobial Properties of Averrhoa bilimbi Extracts at Different Maturity Stages

In previous studies, ethanol extract of Blimbing wuluh have had a hypoglycemic effect, anti-lipid peroxidative, antiatherogenic, and antihypertriglyceridemia in rats induced by streptozotosin. The high content of bioactive compounds in the first stages of fruits might contribute to the antimicrobial properties of the fruits [ 11 ]. At day 19 compared to BUN and creatinine baseline on day 0, they had increased approximately 5 times. The leaves ethanol extract of A.


Seven out of the ten patients required hemodialysis, but fortunately all of them recovered to normal conditions after 2—6 weeks of treatment. In another similar study, crude methanol extract and partitioned fractions of leaves demonstrated significant thrombolytic activity The second most dominant compound, namely Z hexenol is also believed to contribute to the green notes of the fruit.

In normal and alloxan-induced diabetic rats. World Health Organization Fact sheet No. Knowledge of bioactive constituents will provide the bases for developing a new drug from the plant either as a pure compound or standardized extracts using advanced and sophisticated technology.

Young and mature stages of extracts showed a very good antimicrobial activity when compared to ripe stage. Nonanal, nonanoic acid, and E nonenal provide the A.

Among these medicinal plants, A. Selected fruits according to their maturity were cut averghoa halves, and 50 g fruit were weighed and blended with ml water.